The featured SNCA3X iPSC lines are highly sought-after, disease-specific models carrying a triplication of the SNCA gene, closely mimicking the genetic basis of familial Parkinson’s disease. These authenticated human induced pluripotent stem cells serve as powerful tools for studying neurodegeneration, α-synuclein pathology, and autophagy dysfunction in vitro. Researchers utilize these models to differentiate into midbrain dopaminergic neurons, enabling real-time tracking of disease progression and high-throughput drug screening. Backed by ATCC’s rigorous quality control, these standardized cell lines ensure high reproducibility, accelerating therapeutic discovery for Parkinson’s disease.
Learn more: SNCA3x_2KO_C1 – SNCA3x_2KO_C1 | ATCC